Isaac may have been the youngest of these Kirkseys in Chatham Co. When Edward was listed on the tithable list of 1755, he was listed along with two adult males, probably Gideon and Christopher. Therefore, Isaac was not of age in 1755.
In April of 1768, Gideon and his wife sold Isaac a tract of 57 acres. Christopher was a witness. Then in May 1768 Edward sold his 300 acres to Isaac (N. side of Haw River on Pokeberry Creek, known as Cherry Old Field) Orange Co NC Book 3 pages 446-447. This is the same property he sold to Christopher in 1772 (Book A pg 360)
During this time, Isaac is listed on a Role of Capt Isaiah Hogan’s Co. 19 Sep 1772 (NC Militia)
Isaac purchased from John Ellitts and his wife, Mary, in 1773 (Chatham Co Deed Book A p 324), and from Christopher and Perthania property (Deed A 355). This was 165 acres on the north side of the Haw River.
Isaac and Mary sold 57 acres to Christopher in October 1778 (B page 156)
In 1778 Isaac wrote his will naming his wife, Mary, sons: John and Edward and daughter, Sarah. Christopher and Gideon were appointed executors. Moses Smith Jnr, Absalum Smith, an William Hatley, Jnr were witnesses.
Will written in 1778 and probated Feb Court 1779.
Return made after the sale of Isaac’s estate 18 Feb 1786.
In 1784, Gideon Kirksey gave to Isaac Kirksey an orphan son of Isaac Kirksey dec. 239 acres in Chatham Co south side of Wiliasons Creek, Isaac Kirkseys old line, Willliam Griffins line, (Book C p 336)
The family of Isaac moved to South Carolina with Christopher Kirksey’s family.
The timeline makes one wonder if Isaac was ill and making arrangements for his family by disposing of his property.
A copy of Isaac’s will can be read here
#52ancestors
Family History Revisited 
Fascinating research.
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